The main distinguishing symptoms of POTS are: The most common cause of secondary POTS is chronic diabetes mellitus. When this occurs it is known as secondary POTS. POTS can also be the result of another condition. Hyperadrenergic - a less common type of POTS that appears more gradually and to have a genetic component.This can cause the blood to pool in the lower areas of the body This damage affects the peripheral blood vessels and their ability to maintain normal blood pressure when there is more stress from gravity, such as when the patient stands up. Partial dysautonomic - Patients appear to have mild damage to nerves that affect involuntary bodily function (peripheral autonomic neuropathy), such as the heartbeat.POTS is distinguished from other OI syndromes by a rapid increase in the heartbeat of more than 30 beats per minute, or a heart rate that exceeds 120 beats per minute within 10 minutes of standing.
OI occurs when a patient has symptoms of low blood volume when they are standing, which are relieved when they lie down. Postural orthostatic tachycardia syndrome (POTS) is one of a group of conditions characterized by an orthostatic intolerance (OI). When the heart does not operate as it is supposed to, blood may not pump normally throughout the body. The heart muscle is responsible for circulating blood throughout the body.